发育相关蛋白ERCC6L/乙醇致畸因子抗体
产品名称: 发育相关蛋白ERCC6L/乙醇致畸因子抗体
英文名称: ERCC6L
产品编号: bs-6380R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-11-17T15:57:36
使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
